Metaxalonum [Latin]

Metaxalonum [Latin] Brand names, Metaxalonum [Latin] Analogs

Metaxalonum [Latin] Brand Names Mixture

No information avaliable

Metaxalonum [Latin] Chemical_Formula

C₁₂H₁₅NO₃

Metaxalonum [Latin] RX_link

http://www.rxlist.com/cgi/generic/metax.htm

Metaxalonum [Latin] fda sheet

Metaxalonum_[Latin] FDA

Metaxalonum [Latin] msds (material safety sheet)

Metaxalonum [Latin] Synthesis Reference

No information avaliable

Metaxalonum [Latin] Molecular Weight

221.252 g/mol

Metaxalonum [Latin] Melting Point

122 ^oC

Metaxalonum [Latin] H₂O Solubility

No information avaliable

Metaxalonum [Latin] State

Solid

Metaxalonum [Latin] LogP

1.603

Metaxalonum [Latin] Dosage Forms

Tablets (400 mg round, pale rose tablet and an 800 mg oval, pink scored tablet)

Metaxalonum [Latin] Indication

For the treatment of painful musculoskeletal conditions

Metaxalonum [Latin] Pharmacology

Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man.

Metaxalonum [Latin] Absorption

The absolute bioavailability of metaxalone from Skelaxin tablets is not known.

Metaxalonum [Latin] side effects and Toxicity

LD₅₀=775mg/kg (Rat, oral); LD₅₀=1690 mg/kg (Mouse, oral). When determining the LD₅₀ in rats and mice, progressive sedation, hypnosis and finally respiratoryfailure were noted as the dosage increased. In dogs, no LD₅₀ could be determined as the higher doses produced an emetic action in 15 to 30 minutes.

Metaxalonum [Latin] Patient Information

Patient Information:

Use Metaxalone with caution. It may affect driving, operating machinery or other hazarous activities. Metaxalone may increase the effects of alcohol
and other central nervous system depressants.

If you have liver problems or you are breast feeding, discuss with your doctor about the risks of taking the Metaxalone.

Metaxalonum [Latin] Organisms Affected

Humans and other mammals